Zamia

 

Zamia Diaz was a research specialist in the lab from June 2009-June 2012. She graduated from Swarthmore College with a BA in Biology (2009). Zamia is originally from Miami, FL. Zamia went on to pursue her BSN/MSN at the University of Pennsylvania School of Nursing.

Publications

Guo, L.*^, J.R. Mann*, J.C. Mauna°, K.E. Copley°, H. Wang°, J.D. Rubien°, H.M. Odeh, J. Lin, B.L. Lee, L. Ganser, E. Robinson, K.M. Kim, A.C. Murthy, T. Paul, B. Portz, A.M. Gleixner, Z. Diaz, J.L. Carey, A. Smirnov, G. Padilla, E. Lavorando, C. Espy, Y. Shang, E.J. Huang, A. Chesi, N.L. Fawzi, S. Myong, C.J. Donnelly^, and J. Shorter^. (2023). Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains. bioRxiv. doi:10.1101/2023.09.04.555754. pdf file link (*Co-first author. °Co-second author. ^Co-corresponding author).

Guo, L.*, H.J. Kim*, H. Wang*, J. Monaghan°, F. Freyermuth°, J.C. Sung°, K. O’Donovan, C.M. Fare, Z. Diaz, N. Singh, Z.C. Zhang, M. Coughlin, E.A. Sweeny, M.E. DeSantis, M.E. Jackrel, C.B. Rodell, J.A. Burdick, O.D. King, A.D. Gitler, C. Lagier-Tourenne, U.B. Pandey, Y.M. Chook, J.P. Taylor, and J. Shorter. (2018). Nuclear-import receptors reverse aberrant phase transitions of RNA-binding proteins with prion-like domains. Cell. 173(3):677-692. pdf file link (*Co-first author. °Co-second author).

Kim*, H.J., N.C.Kim*, Y.D. Wang*, E.A. Scarborough*, J. Moore*, Z. Diaz*, K.S. MacLea, B. Freibaum, S. Li, A. Molliex, A.P. Kanagaraj, R. Carter, K.B. Boylan, A.M. Wojtas, R. Rademakers, J.L. Pinkus, S.A. Greenberg, J.Q. Trojanowski, B.J. Traynor, B.N. Smith, S. Topp, A.S. Gkazi, J. Miller, C.E. Shaw, M. Kottlors, J. Kirschner, A. Pestronk, Y.R. Li, A.F. Ford, A.D. Gitler, M. Benatar, O.D. King, V.E. Kimonis, E.D. Ross, C.C. Weihl, J. Shorter, and J.P. Taylor^. (2013). Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature. 495:467-473. pdf file link (*Co-first author).

Armakola, M., M.J. Higgins, M.D. Figley, S.J. Barmada, E.A. Scarborough, Z. Diaz, , X. Fang, J. Shorter, N.J. Krogan, S. Finkbeiner, R.V. Farese Jr., and A.D. Gitler. (2012). Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nat. Genet. 44(12):1302–1309. Nat. Genet.44:1302–1309. pdf file link

Couthouis, J., M.P. Hart, R. Erion, Z. Diaz, T. Nakaya, F. Ibrahim, H.J. Kim, J. Mojsilovic-Petrovic, D. Clay-Falcone, L. Elman, L. McCluskey, R. Greene, R.G. Kalb, V.M. Lee, J.Q. Trojanowski, G.A. Nicholson, I.P. Blair, O.D. King, N.M. Bonini, V.M. Van Deerlin, Z. Mourelatos, J. Shorter, and A.D. Gitler. (2012). Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis. Hum. Mol. Genet. 21(13):2899-911. pdf file link

Couthouis, J., M.P. Hart, J. Shorter, M. DeJesus-Hernandez, R. Erion, R.E. Oristano, X.A. Liu, D. Ramos, N. Jethava, D. Hosangadi, J. Epstein, A. Chiang, Z. Diaz, T. Nakaya, F. Ibrahim, H.J. Kim, J.A. Solski, K.L. Williams, J. Mojsilovic-Petrovic, C. Ingre, K. Boylan, N. Graff-Radford, D. Dickson, D. Clay-Falcone, L. Elman, L. McCluskey, R. Greene, R.G. Kalb, V.M.Y. Lee, J.Q. Trojanowski, A.C. Ludolph, W. Robberecht, P.M. Andersen, G.A. Nicholson, I.P. Blair, O.D. King, N.M. Bonini, V. Van Deerlin, R. Rademakers, Z. Mourelatos, and A.D. Gitler. (2011). A yeast functional screen predicts new candidate ALS disease genes. Proc. Natl. Acad. Sci. U.S.A. 108(52):20881-90. pdf file link

Sun, Z.*, Z. Diaz*, X. Fang, M.P. Hart, A. Chesi, J. Shorter and A.D. Gitler. (2011). Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. PLoS Biology. 9(4): e1000614 (*Co-first author). pdf file link

Diaz, Z., K.B. Xavier, and S.T. Miller. (2009). The Crystal Structure of the Escherichia coli Autoinducer-2 Processing Protein LsrF. PLoS ONE 4(8):e6820. pdf link

 

 

 

 

People


Links
 
Department of Biochemistry & Biophysics
p3
University of Pennsylvania